Figure 6.

Quantification of alternative non-homologous end-joining (A-NHEJ) activity

• A, B Percentages of DSBs repaired in increasing time intervals (0.5–2 h, 0.5–6 h, 0.5–24 h) were calculated in XRCC4^wt (A) and XRCC4^m/m (B) cells from the number of γ-H2AX foci in presence or absence of a PARP-1 inhibitor, 3′-AB. **P < 0.01 (XRCC4^m/m + 3′-AB versus XRCC4^m/m + DMSO), two-way ANOVA, Bonferroni post hoc test.