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. 2015 Jul 30;11(7):e1005063. doi: 10.1371/journal.ppat.1005063

Fig 9. Bryostatin-1+JQ1-mediated HIV-1 reactivation is dependent on NF-κB and P-TEFb and independent from NFAT.

Fig 9

The T-lymphoid J-Lat 9.2 (panel A) and monocytic THP89GFP (panel B) cell lines harbor latent HIV-1 provirus containing gfp gene. The cells were pre-treated with the indicated inhibitors for 2 hours and then either mock-treated or treated with the combination bryostatin-1 [10nM]+JQ1 [0.5μM]. At 24 hours post-treatment, cells were analyzed by flow cytometry to quantify the proportion of cells expressing GFP. Means and standard errors of the means from duplicate samples are indicated. One representative experiment from two is represented.