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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Nat Genet. 2015 Jun 15;47(8):955–961. doi: 10.1038/ng.3331

Table 2. deltaSVM predicted causal autoimmune SNPs.

Scoring autoimmune GWAS loci with deltaSVM trained on Th1 yields predictions for high confidence causal SNPs.

Disease Lead SNP Predicted SNP CHR Lead SNP Position Predicted SNP Position Distance Nearset Gene |deltaSVM| Ref.
VIT rs853308 rs860475 chr8 133929917 133929799 −118 TG 16.797 29
VIT rs16872571 rs4697651 chr4 10726853 10721433 −5420 . 13.978 29
T1D rs7020673 rs4380994 chr9 4291747 4282536 −9211 GLIS3 13.591 30
CRO rs6908425 rs7748720 chr6 20728731 20689945 −38786 CDKAL1 13.177 31,32
MS rs1782645 rs1250568 chr10 81048611 81045280 −3331 ZMIZ1 11.039 33
CEL rs1250552 rs1250568 chr10 81058027 81045280 −12747 ZMIZ1 11.039 34
CRO rs10801047 rs6665749 chr1 191559356 191577594 18238 . 10.646 35
CRO rs2797685 rs2797685 chr1 7879063 7879063 0 PER3 10.411 31
Allergy rs962993-T rs962993 chr10 9053132 9053132 0 . 10.008 36
PBC rs10931468 rs3771317 chr2 191538562 191543962 5400 NAB1 9.999 37
CEL rs7753008 rs72928038 chr6 90809639 90976768 167129 BACH2 9.787 38
RA rs72928038 rs72928038 chr6 90976768 90976768 0 BACH2 9.787 39, 40, 33
ATD
MS
MS rs564976 rs485789 chr3 159729059 159730148 1089 AK097161 8.782
MS rs733724 rs733724 chr6 105223864 105223864 0 HACE1 7.360 41
PBC rs3024921 rs3024921 chr2 191943272 191943272 0 STAT4 6.931 42