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Surface cleft-site comparisons between WT-p40PX(PI) and DS-CISK-PX X-ray structures. Expanded view of the phosphoinositide binding sites in WT-p40PX(PI) (A) and DS-CISK-PX (B) domains, respectively, with the phosphoinositide molecule from p40-PX superposed onto the DS-CISK-PX cleft to highlight surface feature similarity.
