Fig. 3. Forest plot of the nine studies comparing STT with alternative regimens of first-line therapy including SET, CT, BCQT and LBT according to ITT analysis (A) and PP analysis (B). The effect of STT was inferior to other therapies with regard to eradication rate. STT, standard triple therapy; SET, sequential therapy; CT, concomitant therapy; BCQT, bismuth-containing quadruple therapy; LBT, levofloxacin-based therapy; CI, confidence interval. The studies concerning SET are as follows: 1) H.G. Park et al., 2012; 2) H.S Choi et al., 2012; 3) H.S Oh et al., 2011; 4) J.W. Chung et al., 2012; 5) W.H. Choi et al., 2008; 6) Y.S. Kim et al., 2011; The study concerning on CT is 7) S.Y. Kim et al., 2013. The study on bismuth-containing quadruple therapy is 8) J.H. Jang et al.,2005. The study concerning levofloxacin-based therapy is 9) K.H. Choi et al., 2011.