TABLE 2.

Steered MD simulations for protein constructs in α-catenin

Constructs (residues)	Domains	Mutation	Type	Velocity/force	Repeats	Trajectory ID
82–635	N-M		cv-SMD	10 Å/ns	2	20–21
82–635	N-M		cv-SMD	5 Å/ns	1	22
273–635	M		cv-SMD	10 Å/ns	4	23–26
273–635	M		cv-SMD	2 Å/ns	2	27–28
273–635	M		cf-SMD	100 pN	2	29–30
273–396	MI		cf-SMD	100 pN	2	31–32
273–396	MI	M371W	cf-SMD	100 pN	1	33