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. 2015 Jul 23;22(7):917–927. doi: 10.1016/j.chembiol.2015.05.016

Table 1.

Activity In Vitro in Latent and Replicating M. tuberculosis Growth and Activity Ex Vivo of the Two Selected Compounds

Compound ID Structure H37Rv MIC (μg/ml) ss18b IC50/IC90 (μg/ml) Intracellular IC50/IC90 (μg/ml)
7904688 graphic file with name fx2.gif 0.5 2.5/20 0.175/0.625
7947882 graphic file with name fx3.gif 0.5 2.5/10 0.625/1.25