Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Main Features of M. tuberculosis Mutants Resistant to 7947882 and 7904688
| M. tuberculosis Strains | MIC (μg/ml) |
WGS Sequencing Results (Amino Acid Change) |
|||
|---|---|---|---|---|---|
| 7947882 | 7904688 | ETH | ethA | pyrG | |
| H37Rv | 0.5 | 0.5 | 1 | – | – |
| 82.14 | >40 | >40 | 10 | T133C (W45R) | T557G (V186G) |
| 82.19 | >40 | >40 | 10 | T386C (L129P) | T557G (V186G) |
| 82.22 | >40 | >40 | 10 | ΔT-94 | T557G (V186G) |
| 88.7 | 5–10 | 10 | 0.5 | – | T557G (V186G) |
| 88.10 | 5–10 | 10 | 0.5 | – | T557G (V186G) |
| 81.10a | >40 | >40 | 10 | Δ1109–1137 | – |
See Table S1.
Laboratory collection.
