Table 4.
Univariate and multivariate analysis of factors influencing overall survival of all 44 patients with epithelioid sarcoma
| Variable | No. of cases | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| 2-year OS rate | 5-year OS rate | p Value | HR | 95 % CI | p Value | ||
| Sex | 0.410 | ||||||
| Male | 30 | 68.1 | 50.0 | ||||
| Female | 14 | 71.4 | 35.7 | ||||
| Age at presentation (years) | 0.704 | ||||||
| ≤30 | 16 | 73.7 | 36.8 | ||||
| >30 | 28 | 67.0 | 51.0 | ||||
| Location | 0.289 | ||||||
| Distal | 20 | 80.0 | 52.5 | ||||
| Proximal | 24 | 60.7 | 38.7 | ||||
| Depth (N = 43) | 0.893 | ||||||
| Superficial | 12 | 66.7 | 33.3 | ||||
| Deep | 31 | 73.1 | 53.6 | ||||
| Tumor size (cm) (N = 39) | 0.335 | ||||||
| ≤5 | 22 | 72.7 | 46.2 | ||||
| >5 | 17 | 63.1 | 36.1 | ||||
| Stage (N = 41) | <0.001 | NS | |||||
| II | 18 | 83.3 | 57.0 | ||||
| III | 12 | 72.7 | 48.5 | ||||
| IV | 11 | 32.7 | 0 | ||||
| N0/1 | 0.008 | NS | |||||
| N0 | 33 | 78.0 | 57.2 | ||||
| N1 | 11 | 45.5 | 11.4 | ||||
| M0/1 | <0.001 | 8.570 | 3.094–23.736 | <0.001 | |||
| M0 | 33 | 81.1 | 57.7 | ||||
| M1 | 11 | 32.7 | 0 | ||||
| Morphological subtype | 0.124 | ||||||
| Classic type | 26 | 80.6 | 53.2 | ||||
| Proximal type | 18 | 52.6 | 32.9 | ||||
| FNCLCC grade | 0.019 | NS | |||||
| 2 | 32 | 74.3 | 56.5 | ||||
| 3 | 12 | 56.2 | 18.7 | ||||
| Surgical margin (N = 32) | 0.396 | ||||||
| Negative | 24 | 78.3 | 56.9 | ||||
| Positive | 8 | 87.5 | 58.3 | ||||
| Adjuvant radiotherapy (N = 33) | 0.704 | ||||||
| Done | 6 | 83.3 | 55.6 | ||||
| Not done | 27 | 80.8 | 58.0 | ||||
| Adjuvant chemotherapy (N = 33) | 0.414 | ||||||
| Done | 3 | 66.7 | 66.7 | ||||
| Not done | 30 | 79.2 | 57.2 | ||||
| Local recurrence (N = 33) | 0.147 | ||||||
| Not occurred | 23 | 81.6 | 62.7 | ||||
| Occurred | 10 | 80.0 | 50.0 | ||||
NS not significant, HR hazard ratios, 95 % CI 95 % confidence interval