Variance level	Group 1 vs	Group 2	Effect size	A priori power	Group 1 N	Group 2 N
2%	let-7B	miR-34a	63.32377903	>99.99%	2*	2*
15%	let-7B	miR-34a	8.443170537	97.06%	2*	2*
28%	let-7B	miR-34a	4.523127073	98.01%	3	3
40%	let-7B	miR-34a	3.166188951	82.2%	3	3

^*With three samples per group, achieved power is >99.99%.