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. 2015 Jul 27;4(7):e161. doi: 10.1038/oncsis.2015.20

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Copyright © 2015 Macmillan Publishers Limited

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Genes silencing and apoptosis. Apoptosis was analyzed by quantification of cleaved caspase-3 level (a and b) and caspase-3/7 activity (c and d) in H295R cells after gene silencing for 5 days without (a and c) and with staurosporin (b and d) for the 6 last hours (50 ng/ml). Histograms in a an b represent the quantification of cleaved caspase-3 proteins from one experiment representative of three independent experiments. Histograms in c and d represent caspase-3/7 activity from three independent experiments.