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. 2015 Jul 31;5:12460. doi: 10.1038/srep12460

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Copyright © 2015, Macmillan Publishers Limited

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(A) The miR-320a expression was significantly increased in K562 after infection with LV-hsa-miR-320a. (B) The BCR/ABL expression was significantly decreased in K562 after infection with LV-hsa-miR-320a. (C) K562 proliferation was significantly reduced after LV-hsa-miR-320a infection compared with cont-miR infection. (D) miR-320a overexpression significantly inhibited the colony-forming ability of K562. (E–G) K562 cell migration, invasion, proliferation and apoptosis were restored after BCR/ABL restoration. The data represent the means ± s.d.; *p < 0.001, **p < 0.05, ***p < 0.01.