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. Author manuscript; available in PMC: 2015 Jul 31.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jun 6;33(8):1952–1959. doi: 10.1161/ATVBAHA.113.301805

Figure 3. Notch inhibition by DAPT disrupts zebrafish intersegmental vessel (ISV) formation but has no effect on the developing caudal vein plexus (CVP).

Figure 3

DMSO-treated (A) and DAPT-treated (B) 48 hpf Tg(kdrl:GFP) zebrafish embryos. Scale bars, 100 μm. Embryos with normal (top inset, A) and defective ISVs (top inset, B), as well as normal (bottom inset, A and B) and defective CVPs, were quantified (C). ###, p≤0.0001 vs. ISV/DMSO. ***, p≤0.0001 vs. ISV/DAPT. Values are percentages.