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The classic appearance of primary biliary cirrhosis in its early portal inflammatory stage demonstrating granulomatous features with interface hepatitis. The inflammatory infiltrate is typically composed of lymphocytes and plasma cells. The lymphocytes may form lymphoid nodules, occasionally with germinal centers. Inflammation typically surrounds the interlobular bile ducts that might show evidence of injury. Abbreviation: H&E (Hematoxylin & Eosin).
