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. 2014 Dec 15;2(4):266–284. doi: 10.14218/JCTH.2014.00024

Fig. 4. Trichrome, X400; Liver biopsy.

Fig. 4

Typical focal lesion of primary sclerosing cholangitis demonstrating “onion skin” concentric fibrosis and chronic periductular inflammation. Notice significant edema in this relatively early phase of fibrosis.