Table 1. Chemotherapy drugs and liver side effects.
Drug | Hepatitis | Cholestasis | Biliary Stricture | Steatosis | Nodular Hyperplasia Fibrosis | Veno-Occlusive Disease |
---|---|---|---|---|---|---|
Actinomycin | Rare | Rare | ||||
Arsenic | ||||||
Asparaginase | Common | Common | ||||
Azathioprine | Rare | Rare | ||||
Bleomycin | Rare | |||||
Bortezomib | Rare | |||||
Busulfan | Rare | Rare | Rare | |||
Capecitabine | Rare | |||||
Carmustine | Common | |||||
Chlorambucil | Rare | |||||
Cyclophosphamide | Rare | Common | ||||
Cytarabine | Rare | Common | ||||
Dacarbazine | Rare | |||||
Docetaxel | Rare | |||||
Doxorubicin | Rare | Rare | Rare | |||
Erlotinib | Common | |||||
Etoposide | Rare | Rare | ||||
Floxuridine | Common | Common | Common | |||
Fluorouracil | Rare | Common | Rare | |||
Gefitinib | Rare | |||||
Gemcitabine | Rare | Rare | ||||
Hydroxyurea | Rare | |||||
Ifosfamide | Rare | |||||
Imatinib | Common | |||||
Interferon | Common | |||||
Interleukin | Common | |||||
Irinotecan | Rare | |||||
Lomustine | Rare | |||||
Melphalan | Rare | Rare | ||||
Mercaptopurine | Rare | Rare | ||||
Methotrexate | Common | Common | ||||
Mitomycin | Rare | Rare | ||||
Oxaliplatin | Rare | Rare | Common | |||
Paclitaxel | Rare | |||||
Pazopanib | Common | |||||
Procarbazine | Rare | |||||
Regorafenib | Rare | |||||
Sorafenib | Rare | Rare | ||||
Streptozocin | Rare | |||||
Thioguanine | Rare | Rare | ||||
Topotecan | Rare | |||||
Vincristine | Rare | |||||
Vinorelbine | Rare |