Table 1. Four GWASs identifying SNPs associated with PEG-IFN/RBV therapy.
Ge et al.4 | Suppiah et al.5 | Tanaka et al.6 | Rauch et al.7 | |
Year | 2009 | 2009 | 2009 | 2010 |
Ancestry | Caucasian/African/Hispanic | Caucasian | Japanese | Caucasian |
Number of patients | 1137 | 293 | 142 | 465 |
SNP | rs12979860 | rs8099917 | rs8099917 | rs8099917 |
Odds ratio | 3.1 | 1.98 | 12.1 | 5.20 |
p value | 1.21×10−28 | 7.06×10−8 | 3.11×10−15 | 5.47×10−8 |
HCV genotype | 1 | 1 | 1 | 1, 2, 3, 4 |