Danielsson |
1994 |
13 |
6–8 mg daily |
Decrease in ALT, AST, IgG |
Complete response: 100% |
Zandieh |
2008 |
9 |
3 mg every other day to 9 mg daily |
Complete response: Normal ALT, AST |
Complete response: 78% No response: 22% |
Wiegand |
2005 |
12 |
Day 1: 6 mg daily Day 2: 9 mg daily Upon remission: 6 mg daily |
Complete remission: AST and ALT drop ≤ two times the upper limit of normal Partial response: ALT or AST ≤ two times the upper limit of normal or AST/ALT improvement > 80% from baseline |
Complete response: 58% Partial response: 25% |
Csepregi |
2006 |
11 |
9 mg daily |
Remission: Absence of symptoms Normal ALT, ALP, IgG |
Treatment-naïve: 57% Treatment-experienced: 100% |
Manns |
2010 |
203 (100 received Budesonide and 103 received prednisone) |
6 mg daily or 9 mg daily |
Complete response: Normal ALT Normal AST Absence of steroid-related side effects |
Budesonide group: 47% Prednisone group: 18.4% |
Czaja |
2000 |
10 |
9 mg daily |
Remission: Asymptomatic Normal or near normal AST Normal bilirubin Normal γ-globulin Failure: Clinical/biochemical deterioration |
Remission: 30%Treatment failure: 40% |