Table 1. Summary of genetic features of Japanese FAD and FTDP-17.

Disease	Genes	Number of mutations	Number of pedigrees	Number of patients
FAD	PSEN1	39	40	140
	PSEN2	0	0	0
	APP	5a	13	35
FTDP-17	MAPT	16	29	84
	GRN	2	2	2

Abbreviations: FAD, familial Alzheimer's disease; FTDP-17, frontotemporal dementia with parkinsonism linked to chromosome 17.

^aAPP duplication was included.