Table 1.
Day 2 | Day 30 | Day 58 | Day 86 | Day 93 | Day 100 | Day 107 | Day 114 | Day 122 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Treatment1 | Mean # of eggs2,3 | % control4 | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control |
Controls | 171.7 | 128.9 | 83.9 | 67.1 | 87.4 | 53.8 | 64.4 | 26.7 | 67.4 | |||||||||
Fluralaner | 0.2a | 99.9 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 | 0.0a | 100 |
112 dogs were used in this study. The 6 dogs in each control group received no treatment. The 6 dogs in the fluralaner group were administered an oral chewable tablet once on Day 0
2Each dog was infested with approximately 200 adult Ctenocephalides felis felis from the KS1 strain on days—2, 7, 28, 56, 84, 91, 105, 112 and 120 post-treatment, flea eggs were collected 48 h post-treatment or post-infestation during a 3-h collection period
3Geometric mean # of eggs recovered from dogs per treatment group
4% control = ((geometric mean count control -geometric mean count treatment)/ geometric mean count treatment)) x 100
ageometric mean of treatment group was significantly different from control (P ≤0.001)