Table 1.
Selected differentially expressed host cell genes in L. m.-infected BMDM
| Selected differentially expressed host cell genes in L. m .-infected BMDM 1 h p.i. | |||
| Gene name (probe set ID) | Symbol | logFC | |
| Additional autophagy-related genes | |||
| BCL2/adenovirus E1B interacting protein 3 (1422470_at) | Bnip3 | 0.417 | |
| Selected differentially expressed host cell genes in L. m .-infected BMDM 24 h p.i. | |||
| Gene name (probe set ID) | Symbol | logFC | |
| LISA | |||
| ATP-binding cassette, sub-family E (OABP), member 1 (1416014_at) | Abce1 | 0.392 | |
| Acyl-CoA synthetase long-chain family member 4 (1418911_s_at) | Acsl4 | 0.347 | |
| AHA1, activator of heat shock protein ATPase homolog 1 (yeast) (1424147_at) | Ahsa1 | 0.422 | |
| Aldolase A, fructose-bisphosphate (1433604_x_at) | Aldoa | 0.496 | |
| Adaptor protein complex AP-2, alpha 2 subunit (1432007_s_at) | Ap2a2 | −0.536 | |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 (1447789_x_at) | Ddx6 | 0.598 | |
| Eukaryotic translation initiation factor 2-alpha kinase 2 (1440866_at) | Eif2ak2 | 0.533 | |
| Enolase 2, gamma neuronal (1418829_a_at) | Eno2 | 0.673 | |
| FUN14 domain containing 1 (1453369_a_at) | Fundc1 | −0.357 | |
| Fusion, derived from t(12;16) malignant liposarcoma (human) (1451285_at) | Fus | 0.397 | |
| Glyceraldehyde-3-phosphate dehydrogenase (1447999_x_at) | Gapdh | 0.506 | |
| Helicase, lymphoid specific (1417541_at) | Hells | 0.505 | |
| Heat shock protein 90, alpha (cytosolic), class A member 1 (1426645_at) | Hsp90aa1 | 0.543 | |
| Potassium channel tetramerisation domain containing 12 (1434881_s_at) | Kctd12 | −0.419 | |
| Lactate dehydrogenase A (1419737_a_at) | Ldha | 0.558 | |
| Microtubule-associated protein 1 light chain 3 beta (1415929_at) | Map1lc3b | −0.445 | |
| Minichromosome maintenance deficient 3 (S. cerevisiae) (1420028_s_at) | Mcm3 | 0.365 | |
| Macrophage migration inhibitory factor (1416335_at) | Mif | 0.731 | |
| Asparaginyl-tRNA synthetase (1428666_at) | Nars | −0.384 | |
| N-myc downstream regulated gene 1 (1420760_s_at) | Ndrg1 | 0.545 | |
| Nuclear factor of activated T cells 5 (1438999_a_at) | Nfat5 | −0.401 | |
| Phosphoglycerate kinase 1 (1417864_at) | Pgk1 | 0.730 | |
| Pyruvate kinase, muscle (1417308_at) | Pkm2 | 0.471 | |
| Protein kinase, AMP-activated, gamma 2 non-catalytic subunit (1423831_at) | Prkag2 | −0.498 | |
| Sorbitol dehydrogenase (1438183_x_at) | Sord | −0.385 | |
| Tripartite motif-containing 21 (1418077_at) | Trim21 | 0.400 | |
| Thioredoxin reductase 1 (1421529_a_at) | Txnrd1 | 0.448 | |
| Zinc finger, CCHC domain containing 11 (1437395_at) | Zcchc11 | −0.477 | |
| Additional autophagy-related genes | |||
| BCL2/adenovirus E1B interacting protein 3 (1422470_at) | Bnip3 | 0.765 | |
| Cathepsin E (1418989_at) | Ctse | −0.852 | |
| DNA-damage regulated autophagy modulator 1 (1424524_at) | Dram1 | 0.445 | |
| Optineurin (1435679_at) | Optn | 0.355 | |
| Syntaxin 5A (1449679_s_at) | Stx5a | −0.429 | |
| Vacuolar protein sorting 41 (yeast) (1437901_a_at) | Vps41 | −0.423 | |
| Glycolysis (GO accession: GO:0006096) | |||
| Fructose-bisphosphate aldolase A (1433604_x_at) | Aldoa | 0.496 | |
| Fructose-bisphosphate aldolase C (1451461_a_at) | Aldoc | 0.636 | |
| Enolase 2 (1418829_a_at) | Eno2 | 0.673 | |
| Glyceraldehyde-3-phosphate dehydrogenase (1447999_x_at) | Gapdh | 0.506 | |
| Lactate dehydrogenase A (1419737_a_at) | Ldha | 0.558 | |
| Phosphoglycerate kinase 1 (1417864_at) | Pgk1 | 0.730 | |
| Phosphoglycerate mutase 1 (1426554_a_at) | Pgam1 | 0.546 | |
| Pyruvate kinase, muscle (1417308_at) | Pkm2 | 0.471 | |
| Protein kinase, AMP-activated, gamma 2 non-catalytic subunit (1423831_at) | Prkag2 | −0.498 | |
| Triosephosphate isomerase 1 (1415918_a_at) | Tpi1 | 0.670 | |
| Immune response (GO accession: GO:0006955) | |||
| BCL2/adenovirus E1B interacting protein 3 (1422470_at) | Bnip3 | 0.765 | |
| Complement component 3 (1423954_at) | C3 | 1.294 | |
| Cell adhesion molecule 1 (1431611_a_at) | Cadm1 | −0.424 | |
| Chemokine (C-C motif) ligand 12 (1419282_at) | Ccl12 | 0.515 | |
| Chemokine (C-C motif) ligand 2 (1420380_at) | Ccl2 | 0.738 | |
| Chemokine (C-C motif) ligand 24 (1450488_at) | Ccl24 | −0.485 | |
| Chemokine (C-C motif) ligand 3 (1419561_at) | Ccl3 | 0.643 | |
| Chemokine (C-C motif) ligand 4 (1421578_at) | Ccl4 | 0.710 | |
| Chemokine (C-C motif) ligand 5 (1418126_at) | Ccl5 | 2.250 | |
| Chemokine (C-C motif) ligand 7 (1421228_at) | Ccl7 | 0.523 | |
| CD180 antigen (1421547_at) | Cd180 | 0.382 | |
| CD28 antigen (1437025_at) | Cd28 | −0.482 | |
| CD300A antigen (1445292_at) | Cd300a | −0.441 | |
| Complement component factor h (1423153_x_at) | Cfh | −0.783 | |
| C-type lectin domain family 5, member a (1421366_at) | Clec5a | 0.804 | |
| Chemokine (C-X3-C) receptor 1 (1450020_at) | Cx3cr1 | −0.379 | |
| Chemokine (C-X-C motif) ligand 1 (1419209_at) | Cxcl1 | 0.808 | |
| Chemokine (C-X-C motif) ligand 10 (1418930_at) | Cxcl10 | 2.023 | |
| Chemokine (C-X-C motif) ligand 11 (1419697_at) | Cxcl11 | 1.205 | |
| Chemokine (C-X-C motif) ligand 13 (1448859_at) | Cxcl13 | 0.360 | |
| Chemokine (C-X-C motif) ligand 9 (1418652_at) | Cxcl9 | 0.698 | |
| DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (1436562_at) | Ddx58 | 0.520 | |
| Guanylate binding protein 1 (1420549_at) | Gbp1 | 1.349 | |
| Guanylate binding protein 2 (1435906_x_at) | Gbp2 | 1.602 | |
| Guanylate binding protein 3 (1418392_a_at) | Gbp3 | 0.919 | |
| Guanylate binding protein 6 (1438676_at) | Gbp6 | 1.507 | |
| Guanylate binding protein 7 (1434380_at) | Gbp7 | 0.459 | |
| Histocompatibility 28 (1421596_s_at) | H28 | 0.777 | |
| Histocompatibility 2, T region locus 24 (1422160_at) | H2-T25 | 0.847 | |
| Intercellular adhesion molecule 1 (1424067_at) | Icam1 | 0.490 | |
| Interferon induced with helicase C domain 1 (1426276_at) | Ifih1 | 0.664 | |
| Immunoglobulin heavy constant mu (1427351_s_at) | Ighm | −0.729 | |
| Interleukin 1 receptor antagonist (1425663_at) | Il1rn | 0.872 | |
| Immunity-related GTPase family M member 1 (1418825_at) | Irgm1 | 0.793 | |
| Kelch-like 6 (Drosophila) (1437886_at) | Klhl6 | −0.637 | |
| Mucosa associated lymphoid tissue lymphoma translocation gene 1 (1456126_at) | Malt1 | 0.578 | |
| Major facilitator superfamily domain containing 6 (1424463_at) | Mfsd6 | −0.602 | |
| Macrophage migration inhibitory factor (1416335_at) | Mif | 0.731 | |
| Myeloid/lymphoid or mixed-lineage leukemia 5 (1434704_at) | Mll5 | −0.401 | |
| Myxovirus (influenza virus) resistance 1 (1451905_a_at) | Mx1 | 1.226 | |
| Myxovirus (influenza virus) resistance 2 (1419676_at) | Mx2 | 0.494 | |
| NA (1416016_at) | NA | 0.347 | |
| NA (1417314_at) | NA | 0.573 | |
| NA (1424775_at) | NA | 0.540 | |
| NA (1439343_at) | NA | −0.416 | |
| NA (1447927_at) | NA | 1.137 | |
| NA (1449009_at) | NA | 1.397 | |
| Neutrophil cytosolic factor 1 (1425609_at) | Ncf1 | −0.491 | |
| 2′-5′ oligoadenylate synthetase 3 (1425374_at) | Oas3 | 0.545 | |
| 2′-5′ oligoadenylate synthetase-like 2 (1453196_a_at) | Oasl2 | 0.762 | |
| ORAI calcium release-activated calcium modulator 1 (1424990_at) | Orai1 | −0.362 | |
| Proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (1422962_a_at) | Psmb8 | 0.424 | |
| RAB27A, member RAS oncogene family (1429123_at) | Rab27a | −0.393 | |
| Radical S-adenosyl methionine domain containing 2 (1421009_at) | Rsad2 | 2.096 | |
| Serine (or cysteine) peptidase inhibitor, clade A, member 3G (1424923_at) | Serpina3g | 0.778 | |
| Tumor necrosis factor (1419607_at) | Tnf | 0.784 | |
| Tumor necrosis factor (ligand) superfamily, member 10 (1459913_at) | Tnfsf10 | 0.495 | |
| Tumor necrosis factor (ligand) superfamily, member 9 (1422924_at) | Tnfsf9 | 0.726 | |
| Chemokine signaling pathway (KEGG entry: mmu04062) | |||
| Adrenergic receptor kinase, beta 1 (1451992_at) | Adrbk1 | −0.420 | |
| Arrestin, beta 2 (1451987_at) | Arrb2 | −0.443 | |
| Chemokine (C-C motif) ligand 12 (1419282_at) | Ccl12 | 0.515 | |
| Chemokine (C-C motif) ligand 2 (1420380_at) | Ccl2 | 0.738 | |
| Chemokine (C-C motif) ligand 24 (1450488_at) | Ccl24 | −0.485 | |
| Chemokine (C-C motif) ligand 3 (1419561_at) | Ccl3 | 0.643 | |
| Chemokine (C-C motif) ligand 4 (1421578_at) | Ccl4 | 0.710 | |
| Chemokine (C-C motif) ligand 5 (1418126_at) | Ccl5 | 2.250 | |
| Chemokine (C-C motif) ligand 7 (1421228_at) | Ccl7 | 0.523 | |
| Chemokine (C-C motif) receptor 1 (1419609_at) | Ccr1 | 0.481 | |
| C-src tyrosine kinase (1423518_at) | Csk | −0.387 | |
| Chemokine (C-X3-C) receptor 1 (1450020_at) | Cx3cr1 | −0.379 | |
| Chemokine (C-X-C motif) ligand 1 (1419209_at) | Cxcl1 | 0.808 | |
| Chemokine (C-X-C motif) ligand 10 (1418930_at) | Cxcl10 | 2.023 | |
| Chemokine (C-X-C motif) ligand 11 (1419697_at) | Cxcl11 | 1.205 | |
| Chemokine (C-X-C motif) ligand 13 (1448859_at) | Cxcl13 | 0.360 | |
| Chemokine (C-X-C motif) ligand 9 (1418652_at) | Cxcl9 | 0.698 | |
| Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog (1442804_at) | Fgr | 0.472 | |
| Neutrophil cytosolic factor 1 (1425609_at) | Ncf1 | −0.491 | |
| Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha (1448306_at) | Nfkbia | 0.500 | |
| Protein kinase, cAMP dependent, catalytic, beta (1420611_at) | Prkacb | −0.434 | |
| Signal transducer and activator of transcription 1 (1450034_at) | Stat1 | 0.784 | |
| Signal transducer and activator of transcription 2 (1421911_at) | Stat2 | 0.413 | |
| Signal transducer and activator of transcription 3 (1426587_a_at) | Stat3 | −0.371 | |