Table 4.

Parameters used for model implementations.

Parameters	Leo et al., 2013 [26]	Nordlund et al., 2009 [39]	In Vivo Implementation
System	Eppendorf tube	NR	Alveolar lining
System volume	4 mL	NR	10 mL/kg BW [41]
ENM type	Ag NP	Silica NP	Ag NP
ENM coating type	Citrate (C)	None	Citrate (C), PVP
Coating molecular weight (mol. wt.)	258	None	258 (C), 10,000 (PVP)
Initial ENM diameter (nm)	20	600	20, 110
ENM density (g/mL)	10.49	2	10.49
ENM concentration (mg/L)	25	3000	NA *
Ionic strength (mM)	0.1	100	245 [43]
pH	3, 5, 7	7.4	7.28 [43]
Initial ENM zeta potential (mV)	−18.2, −22.5, −32.5	−25 [54]	−32.5
Dissolved O${}_{\text{2}}$ (mg/L) **	8.96	8.96	8.96
Temperature	37 ${}^{\circ }$C	22 ${}^{\circ }$C	37 ${}^{\circ }$C
Adsorption probability, α	0.004	0.001	0.004
Steric factor, ${\text{η}}_{\text{S}}$	2.35	1	2.35 (C), 10.6 (PVP)

* In vivo dosage was simulated as inhaled aerosolized ENM present in consumer products [3]; ** saturated O${}_{\text{2}}$ conc. for solutions exposed to atmospheric pressure [25]; values, unless otherwise referenced, are from the original studies; NR = not reported.