Table 2.
Hematology and clinical chemistry data during and after pregnancy
| Analyte | Median (interquartile range) |
|||||
| first trimester | second trimester | third trimester | 1st month after delivery | 2nd month after delivery | nonpregnant | |
| BUN (mg/dL) | 15 (4) | 13 (4)c | 12 (5)c | 23 (8) | 22 (5)c | 15 (6) |
| Glucose (mg/dL) | 65 (20) | 62 (24) | 61 (29) | 66 (21) | 68 (45) | 60 (21) |
| Total protein (g/dL) | 6.8 (0.4) | 6.3 (0.6)c | 5.9 (0.4)c | 7.1 (0.9) | 7.3 (0.5) | 6.9 (0.5) |
| Albumin (g/dL) | 3.9 (0.4) | 3.0 (0.8)c | 2.5 (0.2)c | 3.6 (1.0) | 4.0 (0.5) | 4.0 (0.6) |
| Total bilirubin (mg/dL) | 0.2 (0.1) | 0.2 (0.1) | 0.2 (0.1) | 0.3 (0.1) | 0.2 (0.1) | 0.2 (0.1) |
| Indirect bilirubin (mg/dL) | 0.1 (0.1) | 0.1 (0.0) | 0.1 (0.1) | 0.1 (0.1) | 0.1 (0.0) | 0.1 (0.1) |
| Direct bilirubin (mg/dL) | 0.2 (0.1)a | 0.1 (0.1) | 0.1 (0.1) | 0.2 (0.1) | 0.1 (0.1) | 0.1 (0.1) |
| Creatinine (mg/dL) | 0.8 (0.2) | 0.7 (0.2) | 0.7 (0.3) | 0.8 (0.2) | 0.8 (0.2) | 0.7 (0.3) |
| ALP (U/L) | 96 (44) | 78 (32) | 70 (35) | 135 (48)b | 115 (37) | 86 (48) |
| AST (U/L) | 43 (15) | 49 (14) | 39 (13) | 47 (21) | 48 (20) | 46 (18) |
| ALT (U/L) | 84 (43) | 104 (128) | 85 (63) | 77 (27) | 66 (29) | 83 (62) |
| GGT (U/L) | 38 (19) | 51 (30)a | 43 (29) | 53 (28) | 43 (18) | 37 (21) |
| Creatine kinase (U/L) | 713 (554) | 761 (948) | 691 (356) | 703 (657) | 804 (881) | 757 (652) |
| Calcium (mg/dL) | 8.4 (0.6) | 7.6 (0.5)c | 7.5 (0.5)c | 8.8 (0.8) | 8.7 (0.5) | 8.8 (0.7) |
| Phosphorus (mg/dL) | 3.6 (1.4)a | 3.4 (1.2)c | 3.1 (0.9)c | 4.9 (1.4) | 5.4 (1.3)a | 4.4 (1.4) |
| Sodium (mEq/L) | 145 (2) | 143 (3)c | 142 (2)c | 146 (2) | 146 (4) | 146 (3) |
| Potassium (mEq/L) | 3.6 (0.6) | 3.6 (0.5)a | 3.7 (0.5) | 4.1 (0.4) | 3.9 (0.6) | 3.7 (0.4) |
| Chloride (mEq/L) | 109 (3) | 110 (3) | 110 (3) | 109 (2) | 109 (4) | 109 (4) |
| Total protein cholesterol (mg/dL) | 109 (47)c | 99 (32)c | 103 (22)c | 155 (27) | 129 (38) | 145 (32) |
| Triglycerides (mg/dL) | 65 (17) | 65 (35) | 63 (16) | 71 (30) | 67 (20) | 63 (21) |
| tCO2 (mEq/L) | 18 (2)c | 18 (5)c | 18 (4)c | 21 (4) | 19 (5) | 22 (4) |
| Anion gap | 20 (4) | 19 (5) | 20 (4) | 20 (3) | 21 (4)a | 19 (4) |
| Globulin (g/dL) | 2.9 (0.3) | 3.1 (0.7)a | 3.4 (0.4)c | 3.3 (0.6)b | 3.2 (0.5) | 2.9 (0.5) |
| Lipase (U/L) | 85 (79) | 70 (54)a | 76 (61) | 92 (47) | 94 (34) | 95 (72) |
| Amylase (U/L) | 502 (194)c | 442 (199)c | 489 (129)c | 568 (253) | 553 (213) | 647 (222) |
| WBC (K/uL) | 6100 (3000) | 7700 (3300)b | 8700 (2300)c | 6500 (4300) | 6400 (2100) | 6600 (3000) |
| Neutrophils (/uL) | 3354 (2125) | 4320 (2935)b | 4524 (2004)c | 3025 (2124) | 3744 (1827) | 3418 (2860) |
| Lymphocytes (/uL) | 2160 (1784) | 2613 (2052) | 3300 (1134)b | 2525 (1871) | 2592 (1548) | 2332 (1295) |
| Monocytes (/uL) | 300 (203) | 370 (242) | 412 (256) | 276 (536) | 312 (128) | 338 (294) |
| Eosinophils (/uL) | 0 (61) | 0 (62) | 0 (104) | 17 (81) | 62 (73) | 44 (89) |
| Basophils (/uL) | 0 (0)a | 0 (0) | 0 (0) | 0 (27) | 0 (0) | 0 (26) |
| Platelets (K/uL) | 310 (134) | 266 (160)b | 242 (100)c | 405 (118) | 332 (171) | 337 (113) |
| RBC (M/uL) | 5.88 (0.60) | 5.58 (0.48) | 5.25 (0.63)c | 5.31 (0.99) | 5.48 (0.67) | 5.80 (0.60) |
| Hgb (g/dL) | 13.5 (1.4) | 13.3 (1.1) | 12.8 (1.1)c | 13.1 (2.1) | 13.2 (1.3) | 13.6 (1.4) |
| Hct (%) | 42.5 (3.8) | 41.2 (3.5) | 39.2 (3.7)c | 40.6 (5.3) | 41.0 (3.2) | 42.7 (3.7) |
| MCV (fL) | 73 (4) | 74 (5) | 75 (3) | 77 (6) | 75 (4) | 74 (4) |
| MCH (pg) | 23.4 (1.6) | 23.7 (1.8) | 24.2 (1.3) | 24.5 (1.4) | 23.8 (1.5) | 23.6 (1.6) |
| MCHC (g/dL) | 32.2 (1.3) | 32.1 (1.4) | 32.5 (1.4) | 31.7 (1.9) | 32.0 (1.0) | 32.1 (1.5) |
Value is significantly (aP < 0.05, bP < 0.01, cP < 0.001; Dunn test) different from the nonpregnant age-matched study group.