Table 1.
Cell Line | Source | GI50 (μM) | TGI (μM) | LC50 (μM) | Classificationa |
---|---|---|---|---|---|
ADR-RES | Ovarian | 0.0317 | 30.4 | 100 | Sensitive |
SW-620 | Colon | 0.0469 | 83.75 | 100 | Sensitive |
RPMI-8226 | Leukemia | 0.0527 | 91.2 | 100 | Sensitive |
MOLT-4 | Leukemia | 0.1365 | 15.63 | 100 | Sensitive |
HT29 | Colon | 0.1754 | 8.24 | 72.44 | Sensitive |
CCRF-CEM | Leukemia | 0.3499 | 100 | 100 | Sensitive |
HCT-116 | Colon | 0.3784 | 100 | 100 | Sensitive |
NCI-H460 | Lung | 0.4355 | 38.28 | 100 | Sensitive |
TK-10 | Renal | 21.18 | 73.96 | 100 | Resistant |
HOP-92 | Lung | 25.47 | 73.96 | 100 | Resistant |
NCI-H322M | Lung | 35.32 | 100 | 100 | Resistant |
HOP-62 | Lung | 46.13 | 100 | 100 | Resistant |
SK-OV-3 | Ovarian | 66.22 | 100 | 100 | Resistant |
EKVX | Lung | 88.72 | 100 | 100 | Resistant |
MDA-MB-231 | Breast | 100 | 100 | 100 | Resistant |
HS 578T | Breast | 100 | 100 | 100 | Resistant |
Cell lines with a GI50 < 0.5 μM were classified as sensitive; cell lines with a GI50 > 20 μM were classified as resistant.