. Author manuscript; available in PMC: 2015 Jul 31.

Published in final edited form as: Crit Rev Toxicol. 2015 Jan;45(1):1–43. doi: 10.3109/10408444.2014.973934

Table 5.

Cyp1a1 and Cyp1b1 gene expression in mouse lung and liver exposed to 5, 50, 150, and 300 mg/kg-bw/day BaP for three days and excised 4 or 24 hours post-exposure. Those not statistically significant are indicated by ns.

	Dose (mg/kg-bw/day)	LUNG (fold change)		LIVER (fold change)

		4 hours	24 hours	4 hours	24 hours
*Cyp1a1*	5	↑46.9	↓7.5	↑25.5	ns
	50	↑103.3	↓1.5	↑109.9	ns
	150	↑179.3	↑14.7	↑146.7	ns
	300	↑210.1	↑42.9	↑165.4	↑9.0

*Cyp1b1*	5	↑10.4	↑1.5	ns	ns
	50	↑23.5	↑1.7	ns	ns
	150	↑161.2	↑21.8	ns	ns
	300	↑208.6	↑28.6	ns	ns