Table 4.
Univariate and multivariate logistic regression models of factors associated with Chronic Obstructive Pulmonary Disease among HIV-infected adults at the Jos University Teaching Hospital HIV Clinic (May 2013-March 2014)
| Characteristic | Univariate Analysis | Multivariate | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Age, years | <0.01 | 0.01 | ||||
| 30-40 | Ref. | Ref. | ||||
| >40-50 | 1.21 | 0.55-2.66 | 0.64 | 1.33 | 0.57-3.14 | 0.51 |
| >50 | 3.41 | 1.51-7.69 | <0.01 | 3.40 | 1.42-8.17 | 0.01 |
| Gender | ||||||
| Female | Ref. | |||||
| Male | 1.61 | 0.90-2.86 | 0.11 | - | - | - |
| Duration of cigarette smoking (Years) | 0.09 | |||||
| < 1 | Ref | |||||
| 1-20 | 0.94 | 0.37-2.36 | 0.89 | - | - | - |
| >20 | 3.69 | 1.13-11.59 | 0.03 | - | - | - |
| Duration of biomass exposure (years) | 0.20 | |||||
| <1 | Ref | |||||
| 1-20 | 0.91 | 0.47-1.75 | 0.70 | - | - | - |
| 20 | 1.93 | 0.88-4.22 | 0.10 | - | - | - |
| History of PTB | ||||||
| No | Ref. | |||||
| Yes | 0.76 | 0.40-1.47 | 0.42 | - | - | - |
| On ART | ||||||
| No | Ref. | - | ||||
| Yes | 1.85 | 0.37-9.44 | 0.46 | - | - | - |
| Current CD4 T-cell count, cells/μl | ||||||
| ≥200 | Ref | Ref | 0.09 | |||
| <200 | 2.53 | 1.14- 5.63 | 0.02 | 2.17 | 0.88 – 5.36 | |
| Current HIV Viral Load | ||||||
| Undetectable | Ref. | - | ||||
| Detectable | 0.97 | 0.52-1.83 | 0.93 | - | - | - |
PTB- Pulmonary Tuberculosis; ART- Antiretroviral therapy; OR-Odds ratio