Table 1.
Number, gender | Age at first symptoms (years) | Age at Ds (years)/Ds delay (months) | Age at onset (years) |
Nocturnal sleep disturbance | HLA test | Initial/posterior BMI | Treatment after Ds | |||
---|---|---|---|---|---|---|---|---|---|---|
Sleepiness | Cataplexy | Hallucinations | Sleep paralysis | |||||||
1, F | 7 | 9/24 | 7 | 11 | 17 | – | No | DQB1⁎06:02/DRB⁎15 | P90–95/P90–95 | M |
2, F | 9 | 10/8 | 9 | 9 | 9 | – | Yes | DQB1⁎06:02/DRB⁎15 | P90–95/P95–97 | M+V |
3, M | 8 | 8/4 | 8 | 8 | – | 9 | Yes | DQB1⁎06:02/DRB⁎15 | P90–95/P97 | M+V |
4, M | 6 | 8/14 | 6 | – | – | – | No | DQB1⁎06:02/DRB⁎15 | P85–90/P75–85 | M |
5, M | 10 | 11/9 | 10 | 11 | – | – | Yes | DQB1⁎06:02/DRB⁎15 | P95–97/P>97 | M+V |
6, F | 6 | 9/24 | 6 | – | 9 | – | Yes | DQB1⁎06:02/DRB⁎15 | P75/P25–50 | M |
7, M | 10 | 11/15 | 10 | – | – | – | Yes | DQB1⁎06:02 | P85–90/P75–85 | M |
8, M | 7 | 9/24 | 7 | 9 | – | – | Yes | DQB1⁎06:02/DRB⁎15 | P75–85/P85 | M+V |
Total (median) | 6–10 (8) | 8–11 (9)/4–24(14) | 6–10 (8) | 8–11 (9) | 9–17 (9) |
Ds – diagnosis; BMI – Body Mass Index; M – Methylphenidate; V – Venlafaxine.