Table 1. Baseline characteristics of 300 chronic hepatitisB patients.
| Patient Characteristic | All Patients(n = 300) | HBeAg-positive (n = 177) | HBeAg–negative (n = 123) | ||||
|---|---|---|---|---|---|---|---|
| PNALT(ALT≤40 U/L) | Minimally elevated ALT(ALT > 40 U/L) | P-value | PNALT(ALT≤40 U/L) | Minimally elevated ALT(ALT > 40 U/L) | P-value | ||
| Mean age | 36(28–43) | 30(25–41) | 30(26–39) | NS | 41.76±9.55 | 42.94±9.72 | NS |
| Male | 218(72.67%) | 29(58%) | 88(69.29%) | NS | 41(80.39%) | 60(83.33%) | NS |
| ALB (g/L) | 43(40–45) | 43(40–45) | 42(40–45) | NS | 43.20±3.45 | 42.57±3.53 | NS |
| GLB (g/L) | 33(30–36) | 32(31–36) | 34(30–36) | NS | 31.86±3.56 | 33.18±4.36 | NS |
| ALT(U/L) | 51(35–66) | 32(26–37) | 62(52–71) | < 0.001 | 26.90±7.34 | 57(51–69) | <0.001 |
| AST(U/L) | 51(35–66) | 29(23–35) | 41(34–52) | < 0.001 | 25(22–28) | 40(33–52) | <0.001 |
| WBC (×10 9 /L) | 5.40(4.60–6.30) | 5.48±1.34 | 5.60(4.80–6.60) | NS | 5.30(4.70–6.20) | 5.30(4.23–6.20) | NS |
| PLT (×10 9 /L) | 175.07±54.24 | 189.46±65.62 | 178.39±48.53 | NS | 167.45±54.59 | 164.61±53.11 | NS |
| PT (s) | 13.00(12.50–13.60) | 12.75(12.40–13.20) | 13.00(12.50–13.80) | 0.036 | 13.00(12.50–13.50) | 13.05(12.40–13.50) | NS |
| AFP(ng/mL) | 2.88(2.04–4.26) | 2.44(1.87–3.38) | 2.30(3.26–4.50) | 0.007 | 2.34(1.86–3.08) | 3.46(2.40–5.62) | < 0.001 |
| HBV DNA (log IU/mL) | 6.12(4.52–7.25) | 7.10(5.55–7.95) | 7.14(6.17–8.11) | NS | 4.18(3.25–4.44) | 5.03±1.05 | < 0.001 |
Continuous variables are expressed as mean ±SD or median and interquartile range, and categorical variables are described by count and proportions. Abbreviations: PNALT, persistent normal ALT; ALB, albumin; GLB, globulin, ALT, alanine aminotransferase; AST, aspartate aminotransferase; WBC, white blood cells; PLT, platelet; PT, prothrombin time;AFP, α-fetoprotein; HBV, hepatitis B virus; NS, not significant.