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. 2015 Jul 31;10(7):e0134523. doi: 10.1371/journal.pone.0134523

Fig 4. Correlation analysis of the numbers of different subsets of circulating memory Tfh cells and the values of clinical measures in MS patients.

Fig 4

(A-B) The numbers of ICOS+ and CCR7+ICOS+ memory Tfh cells were positively associated with the EDSS scores in MS patients. (C-D) The numbers of ICOS+ and CCR7+ICOS+ memory Tfh cells were positively associated with the levels of plasma IL-21. (E-F) The numbers of CCR7+ICOS+ memory Tfh cells were positively correlated with the levels of CSF IL-21 and CSF IgG. (G-H) The numbers of CCR7+ICOS+ memory Tfh cells were positively correlated with the levels of CSF MBP-Ab and CSF MOG-Ab.