Table 2. The demographic and clinical features of MS patients and NND who received a lumbar puncture.
MS | NND | |
---|---|---|
n | 15 | 10 |
Age (year) | 36 (23–56) | 37 (27–50) |
Female/male | 13/2 | 9/1 |
7—headache | ||
Diagnosis | MS | 3—seizure |
CSF WBC (106/L) | 11 (1–37) * | 1.5 (0–6) |
CSF proteins (g/L) | 0.36 (0.28–0.65) * | 0.29 (0.16–0.41) |
CSF IgG (mg/l) | 47.9 (17.1–149) * | 22 (10–32) |
Plasma MBP-Ab (OD value) | 0.152 (0.062–3.288) | |
CSF MBP-Ab (OD value) | 0.11 (0.055–0.381) | |
Plasma MOG-Ab (OD value) | 0.167 (0.065–3.363) | |
CSF MOG-Ab (OD value) | 0.081 (0.056–0.308) |
Data shown are median and range, except specified. CSF: Cerebrospinal fluid; MBP-Ab: Antibodies against myelin basic protein; MOG-Ab: Antibodies against myelin oligodendrocyte glycopotein; NND: Non-inflammatory neurological diseases; OD: Optical density; WBC: White blood cell. Normal values: CSF WBC, 0–8 ×106/L; CSF proteins, 0.15–0.45 g/L; CSF IgG, 0–34 mg/l; Plasma MBP-Ab < 0.75; CSF MBP-Ab < 0.65; Plasma MOG-Ab < 0.64; CSF MOG-Ab < 0.56. *P<0.05 vs. the HC.