Fig 4. Effects of XOR inhibitors on gene expression after global brain I/R injury.
The mRNA levels are given as the mean ± SD normalized to β-actin level for each sample. (n = 7)*P<0.05, **P<0.01 vs. control. #P<0.05 vs. methylcellulose. IL1β; interleukin-1β, TNF-α; tumor necrosis factor-α, ICAM-1; intercellular adhesion molecule-1, MMP-9; matrix metalloproteinase-9, Xdh; xanthine dehydrogenase, C; Control, M; Methylcellulose, A; Allopurinol, F; Febuxostat.