Table 2. Clinical and demographic parameters of the study population.

Four time-points within a one-year follow-up were considered.

Time-point		One week	One month	5 months	One year
Creatinine serum concentration (mg/dL)		2.48 ± 2.07	1.69 ± 0.93	1.49 ± 0.72	1.38 ± 0.62
eGFR (ml min-1 1.73 m-2)		33.29 ± 14.10	36.90 ± 13.73	41.60 ± 13.98	44.02 ± 14.83
Recipients on tacrolimus	208 (80.3)
Dose (mg/kg)		0.14 ± 0.07	0.11 ± 0.06	0.08 ± 0.04	0.06 ± 0.06
Dose-normalized Tac blood concentration (ng/ml per mg/day per kg)		111.0 ± 80.1	121.1 ± 66.7	162.5± 77.0	176.3 ± 110.1
Recipients on cyclosporine	51 (19.7)
Dose (mg/kg)		8.0 ± 1.9	6.3 ± 1.6	4.5 ±1.7	3.5 ± 1.1
Dose-normalized CsA blood concentration (ng/ml per mg/day per kg)		42.32 ± 20.13	53.91 ± 22.48	51.04 ± 17.96	50.16 ± 18.98
Recipients sex (male/female)	158 (61.0) / 101 (39.0)
Recipients age (years)	48.18 ± 14.31
Type of dialysis (hemodialysis/peritoneal)	174 (67.2)/85 (32.8)
Duration of dialysis before transplantation (months)	38.16 ± 30.09
Donor age (years)	47.63 ± 17.51
Number of transplants (first/second/third)	246 (95.0)/11 (4.2)/1 (0.8)
Cold ischemia time (hours)	16.22 ± 5.01
Peak cytotoxic PRA ≥ 50%	20 (7.72)
HLA mismatch
0–2	69 (26.64)
3–4	162 (62.54)
5–6	28 (10.81)

Data are shown as number (percentage) or mean ± standard deviation.