Table 1. Clinical, biological, thoracolumbar X ray and genetic characteristics of 232 patients with PsA, serum tested for ANA at 1: 100.
| Characteristics | Total n = 232 | ANA + n = 132 | ANA − n = 100 | p value |
|---|---|---|---|---|
| Gender | ||||
| women | 159 (69%) | 99 (75%) | 60 (60%) | p<0.02 |
| men | 73 (31%) | 33 (25%) | 40 (40%) | NS |
| Age at blood sample (average, min-max) | 46 (18–70) | 46 (18–78) | 47 (18–70) | NS |
| Age at onset PsA (average, min-max) | 40 (18–65) | 41 (16–65) | 40 (15–65) | NS |
| Duration of PsA (average, min-max) | 5 (0–37) | 5 (0–24) | 6 (0–37) | NS |
| Psoriasis (personal history) n (%) | 194 (83%) | 110 (83%) | 84 (84%) | NS |
| Arthritis pattern at assessment, n (%) | ||||
| dactylitis | 56 (24%) | 28 (21%) | 28 (28%) | NS |
| peripheral | 71 (30%) | 46 (34%) | 25 (25%) | p<0.2 |
| axial only | 21 (9%) | 13 (6%) | 8 (4%) | NS |
| axial and peripheral | 127 (55%) | 68 (30%) | 60 (26%) | NS |
| unknown | 13 (6%) | 5 (2%) | 8 (3%) | NS |
| Axial syndesmophytes on thoracolumbar X ray | 23 (10%) | 13 (10%) | 10 (10%) | NS |
| Biological features (%) | ||||
| RF + | 34 (15%) | 23 (17%) | 11 (11%) | NS |
| Anti Ds DNA + | 0 | 0 | 0 | NS |
| Anti SSA | 3 (0.5%) | 3 (0.5%) | 0 | NS |
| Anti SSB | 0 | 0 | 0 | NS |
| Anti RNP | 0 | 0 | 0 | NS |
| Anti CCP + (>50UI/L) | 4 (1.7%) | 2 (0.5%) | 2 (0.5%) | NS |
| HLA-B27 | 16% | 16,80% | 15% | NS |
| HLA-DR Shared Epitope | 36% | 35% | 38% | NS |
| HLA-DR7 | 31% | 34% | 27% | NS |
| HLA-CW6 | 29% | 31% | 26% | NS |