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. 2015 Jul 31;10(7):e0133403. doi: 10.1371/journal.pone.0133403

Table 1. Clinical data of patients who did or did not progress to cancer.

Cancer No Cancer p-value
Parameter N = 32 patients N = 181 patients
Mean Age at baseline (years) 65.6 62.5 0.16
Gender (M:F ratio) 4.3:1 3.8:1 0.77
Mean BE length at baseline (cm) (min-max) 8.22 (2–19) 5.26 (0–20) <0.001
Maximum diagnosis at baseline
 Negative for dysplasia 5 144
 Indefinite 0 0
 LGD 3 27
 HGD 24 10 <0.001
Mean # of biopsies/pt (min-max) 26.6 (4–64) 11.8 (1–43) <0.001
Mean # crypts*/biopsy (median, min-max) 13.7 (13, 0–47) 13.6 (12, 1–113) 0.73
Mean # Nondysplastic crypts/biopsy (median, min-max) 8.9 (8, 0–45) 12.7 (11, 0–113) <0.001
Mean # Dysplastic crypts/biopsy (median, min-max) 4.8 (0, 0–47) 0.9 (0, (0–39) <0.001
Mean (median, min-max) follow-up in months 41.3 (31, 2.9–118) 98.4 (107.1,2.3–176) <0.001

* combined nondysplastic and dysplastic