Table 1. Clinical data of patients who did or did not progress to cancer.
Cancer | No Cancer | p-value | |
---|---|---|---|
Parameter | N = 32 patients | N = 181 patients | |
Mean Age at baseline (years) | 65.6 | 62.5 | 0.16 |
Gender (M:F ratio) | 4.3:1 | 3.8:1 | 0.77 |
Mean BE length at baseline (cm) (min-max) | 8.22 (2–19) | 5.26 (0–20) | <0.001 |
Maximum diagnosis at baseline | |||
Negative for dysplasia | 5 | 144 | |
Indefinite | 0 | 0 | |
LGD | 3 | 27 | |
HGD | 24 | 10 | <0.001 |
Mean # of biopsies/pt (min-max) | 26.6 (4–64) | 11.8 (1–43) | <0.001 |
Mean # crypts*/biopsy (median, min-max) | 13.7 (13, 0–47) | 13.6 (12, 1–113) | 0.73 |
Mean # Nondysplastic crypts/biopsy (median, min-max) | 8.9 (8, 0–45) | 12.7 (11, 0–113) | <0.001 |
Mean # Dysplastic crypts/biopsy (median, min-max) | 4.8 (0, 0–47) | 0.9 (0, (0–39) | <0.001 |
Mean (median, min-max) follow-up in months | 41.3 (31, 2.9–118) | 98.4 (107.1,2.3–176) | <0.001 |
* combined nondysplastic and dysplastic