Table 2. Results of univariate analysis regarding goblet cell parameters in patients who did or did not progress to cancer.

Goblet Cell (GC) Parameters	All Biopsies			Biopsies with Dysplastic Crypts			Biopsies without Dysplastic Crypts
	NC	C		NC	C		NC	C
	n = 2138	n = 850	P-value ǂ	n = 163	n = 297	P-value ǂ	n = 2048	n = 625	P-value ǂ
Number of Goblet Cells
median (range)	44 (0–1260)	12 (0–914)		6 (0–256)	3 (0–556)		46 (0–1260)	19 (0–914)
absent	438	249	<0.0001	58	121	0.0420	412	159	0.0070
1–30	493	283		56	122		465	191
31–60	258	87		18	22		248	70
61–90	199	60		17	12		185	50
91–120	145	32		5	9		139	23
>120	605	139		9	10		594	128
Number of Crypts With ≥ One Goblet Cell
median (range)	7 (0–45)	3 (0–45)		2 (0–32)	1 (0–18)		7 (0–45)	4 (0–45)
absent	436	250	<0.0001	60	126	0.0590	409	155	0.0160
1–5	473	289		57	135		451	186
6–10	433	128		25	27		418	113
>10	793	182		21	7		763	166
Number of Goblet Cells/crypt
median (range)	4.1 (0–106)	1.1 (0–49.75)		0.6 (0–22)	0.18 (0–44)		4.3 (0–106)	1.9 (0–56.4)
absent	434	246	<0.0001	58	121	0.0420	412	159	0.0070
>0–3	518	312		52	129		482	197
4–6	323	94		28	24		302	82
7–9	245	64		12	8		236	55
10–12	166	45		5	6		166	41
>12	448	84		8	8		445	87
Proportion of Crypts With ≥ Goblet Cell
median (range)	0.86 (0–1)	0.25 (0–1)		0.37 (0–1)	0.07 (0–1)		0.9 (0–1)	0.5 (0–1)
absent	432	247	<0.0001	60	126	0.0590	409	155	0.0160
0–30%	246	204		39	114		213	96
30–60%	203	106		12	26		192	82
>60%	1,250	287		52	29		1,227	287

NC = No cancer

C = Cancer

^ǂ p-value: test for the risk difference between absent/present of the feature