Table 1. The correlations between IHC expression levels of PAI-1, PAI-2, uPA, uPAR, MMP-2, and MMP-9 analyzed by Spearman’s rank correlation analysis in derivation cohort with 98 NSCLC cases.
| PAI-2 | PAI-1 | uPA | uPAR | MMP-2 | MMP-9 | |
|---|---|---|---|---|---|---|
| PAI-2 | 1 | |||||
| PAI-1 | -0.142 | 1 | ||||
| uPA | -0.246* | 0.616** | 1 | |||
| uPAR | -0.062 | 0.431** | 0.571** | 1 | ||
| MMP-2 | -0.142 | 0.175 | 0.261** | 0.109 | 1 | |
| MMP-9 | -0.080 | 0.197 | 0.354** | 0.322** | 0.126 | 1 |
**Correlation is significant at the 0.01 level (2-tailed).
*Correlation is significant at the 0.05 level (2-tailed).
PAI-1: plasminogen activator inhibitor-1; PAI-2: plasminogen activator inhibitor-2; uPA: urokinase-type plasminogen activator; uPAR: urokinase-type plasminogen activator receptor; MMP-2: matrix metalloproteinase 2; MMP-9: matrix metalloproteinase 9.