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. Author manuscript; available in PMC: 2016 Jan 30.
Published in final edited form as: Nature. 2015 Jul 22;523(7562):561–567. doi: 10.1038/nature14656

Extended Data Fig. 13. A possible role of the arrestin C-edge in lipid binding.

Extended Data Fig. 13

a,b The asymmetric assembly of the rhodopsin-arrestin complex in the presence of a lipid membrane bilayer, showing the C-edge of arrestin dipping into the lipid layer.

c,d, A close-up view of the C-edge of arrestin in the membrane layer, where the conserved hydrophobic side chains are shown. The figure was made using the computational model for the full rhodopsin-arrestin complex.