Histology volume reconstruction, ; (a) cut through shows the 3D continuity of the lung outline (brown), airways (blue outline, see arrow), and inflammation (yellow); (b) same as (a) with completely reconstructed airways (purple) and blood vessels (red); arrows point to reduced zig-zag pattern which is a qualitative indication of a good alignment; (c) overlay of and ex vivo MRI, (green); (d) alignment of airways, histology (purple), ex vivo MRI (green).