. 2015 Aug 1;13:116. doi: 10.1186/s12955-015-0306-5

Table 3.

Differences in the I-QOL and IUI scores according to the Treatment Benefit Scale (TBS) at week 12

	Treatment benefit scale	Number	Mean	SD	95 % CI for mean		p-value
	Treatment benefit scale	Number	Mean	SD	Lower	Upper	p-value
I-QOL scale score	Greatly improve	187	77.49	20.70	74.51	80.48	<0.001
	Improved	274	57.36	22.69	54.67	60.06
	Not changed^a	464	37.21	20.42	35.35	39.08
	Worsened^a	109	31.46	19.95	27.67	35.25
Scale score of the abbreviated form of the I-QOL	Greatly improve	187	72.19	20.77	69.20	75.19	<0.001
	Improved	274	54.71	19.97	52.33	57.08
	Not changed^a	464	37.95	19.23	36.20	39.71
	Worsened^a	109	33.58	18.64	30.04	37.12
IUI scores	Greatly improve	187	0.60	0.27	0.56	0.64	<0.001
	Improved	274	0.39	0.20	0.37	0.42
	Not changed^a	464	0.24	0.16	0.23	0.25
	Worsened^a	109	0.21	0.14	0.18	0.23

^aAfter applying Bonferroni’s correction, all comparisons established by TBS levels were significant with the exception of that between not changed vs worsened levels