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. 2015 Aug 1;34(1):74. doi: 10.1186/s13046-015-0188-8

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© van den Hoven et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Catheter-related particle flow-dynamics. Composite figure of the fluorescent microsphere administrations with the SMC (a) and ARC (b) Images of fluorescent microsphere administrations were created by overlaying frames from a representative part of the experiment 3 video (Additional file 1: Movie S1), to show the typical catheter-related particle flow pattern. The background of images (a) and (b) was edited in Adobe Photoshop to emphasize an area of interest. a Off-centered SMC position, laminar outflow pattern and absence of microsphere flow towards the LHA. b Centro-luminal ARC position, turbulent outflow pattern (note the eddy current adjacent to the ARC tip) and more homogenous microsphere distribution over the LHA and RHA