Table 2.
Associations between CXCR2 expression and pathological background factors
| All patients | CXCR2-positive | CXCR2-negative | p value | ||
|---|---|---|---|---|---|
| (n = 82) | (n = 33) | (n = 49) | |||
| pT factor | 1 | 40 (48.8 %) | 12 (36.4 %) | 28 (57.1 %) | 0.06 |
| 2 | 10 (12.2 %) | 7 (21.2 %) | 3 (6.1 %) | ||
| 3 | 32 (39.0 %) | 14 (42.4 %) | 18 (36.7 %) | ||
| pN factor | 0 | 31 (37.8 %) | 12 (36.4 %) | 19 (38.8 %) | 0.83 |
| 1 | 51 (62.2 %) | 21 (63.6 %) | 30 (61.2 %) | ||
| Histological stage | I | 24 (29.3 %) | 9 (27.3 %) | 15 (30.6 %) | 0.95 |
| IIA | 7 (8.5 %) | 3 (9.1 %) | 4 (8.2 %) | ||
| IIB | 24 (29.3 %) | 9 (27.3 %) | 15 (30.6 %) | ||
| III | 27 (32.9 %) | 12 (36.4 %) | 15 (30.6 %) | ||
| Histological type | Well | 17 (20.7 %) | 7 (21.2 %) | 10 (20.4 %) | 0.65 |
| Moderately | 57 (69.5 %) | 24 (72.7 %) | 33 (67.3 %) | ||
| Poorly | 8 (9.8 %) | 2 (6.1 %) | 6 (12.2 %) | ||
| Infiltrative growth pattern | INF-a | 6 (7.3 %) | 3 (9.1 %) | 3 (6.1 %) | 0.86 |
| INF-b | 69 (84.1 %) | 27 (81.8 %) | 42 (85.7 %) | ||
| INF-c | 7 (8.5 %) | 3 (9.1 %) | 4 (8.2 %) | ||
| Lymphatic invasion | (+) | 65 (79.3 %) | 27 (81.8 %) | 38 (77.6 %) | 0.64 |
| (−) | 17 (20.7 %) | 6 (18.2 %) | 11 (22.4 %) | ||
| Venous invasion | (+) | 39 (47.6 %) | 18 (54.5 %) | 21 (42.9 %) | 0.30 |
| (−) | 43 (52.4 %) | 15 (45.5 %) | 28 (57.1 %) | ||
INF-a, expansive growth of tumor nests with a well-demarcated border from surrounding tissue; INF-b, intermediate growth pattern, between INF-a and c; INF-c, infiltrative growth of tumor nests with an ill-defined border from surrounding tissue