. 2015 Aug 1;16:326. doi: 10.1186/s13063-015-0843-6

Table 2.

Outcome measures and measurement points

OUTCOME	TIMELINE
	Screening	Baseline	3 months	6 months	12 months	18 months	24 months
Informed Consent	X
Inclusion/Exclusion Criteria	X
Medical History/Demographics	X
Adverse Events Recorded		X	X	X	X	X	X
Physical function measures
Short Physical Performance Battery		X	X	X	X		X
Hand Grip Strength		X	X	X	X		X
Six Minute Walk Test		X	X	X	X		X
Blood measures
Sodium	X	X	X	X	X		X
Potassium	X	X	X	X	X		X
Creatinine	X	X	X	X	X		X
Urea	X	X	X	X	X		X
Bicarbonate	X	X	X	X	X		X
Estimated GFR	X	X	X	X	X		X
Calcium		X	X	X	X		X
Phosphate		X	X	X	X		X
Alkaline phosphatase		X	X	X	X		X
Magnesium		X	X	X	X		X
Albumin		X	X	X	X		X
Haemoglobin		X	X	X	X		X
Thyroid function		X	X	X	X		X
HbA1c		X	X	X	X		X
Total Cholesterol		X	X	X	X		X
Cystatin C		X	X	X	X		X
Study Biobank Samples		X	X	X	X		X
Urine Sample
Protein/creatinine ratio		X	X	X	X		X
Albumin/creatinine ratio		X	X	X	X		X
Questionnaires
EQ-5D		X	X	X	X		X
KDQoL		X	X	X	X		X
Health Diary		X	X	X	X		X
Falls Diary		X^a	X	X	X	X	X
Anthropometric Measurements
Mid-arm Circumference		X	X	X	X		X
Triceps Skin Fold Thickness		X	X	X	X		X
Mid-thigh Circumference		X	X	X	X		X
Height		X
Weight		X	X	X	X		X
Vascular measures
Blood pressure and pulse	X	X	X	X	X		X
B-type natriuretic peptide		X			X		X
Bone and calcium metabolism
Calcium		X	X	X	X		X
Phosphate		X	X	X	X		X
Parathyroid hormone		X			X		X
25-hydroxyvitamin D		X			X		X
1,25 hydroxyvitamin D		X			X		X
Tartrate-resistant acid phosphatase-5b		X			X		X
Bone-specific alkaline phosphatase		X			X		X

^aadministered at baseline but not recorded until 3 months