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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Immunol Methods. 2015 Apr 7;423:52–59. doi: 10.1016/j.jim.2015.03.019

Figure 3.

Figure 3

Human erythroid cell maturation

Erythroid cells display a number of changes as they mature. Early cells are nucleated and display CD71 and CD235a. As cell mature they lose CD71 and eventually become enucleated. After enucleation RNA is retained in reticulocytes but is also lost as cells become mature erythrocytes. Shaded area show cells with a nucleus.