Table 3.
Knee pain severity and history of injury predict a new knee injury within 12 months
| Frequency of Injuries/Total Observations | Unadjusted Odds Ratio for Injury | Adjusted* Odds Ratio for Injury | |
|---|---|---|---|
| Full Osteoarthritis Initiative (4,435 participants, 877 injuries) | |||
| No Ipsilateral Knee Pain (WOMAC ≤ 2) | 441/22188 (2.0%) | Reference | Reference |
| Ipsilateral Knee Pain (WOMAC ≥ 3) | 436/9292 (4.7%) | 2.25 (1.96, 2.59) | 1.94 (1.66, 2.26) |
| No Contralateral Knee Pain (WOMAC ≤ 2) | 536/22187 (2.4%) | Reference | Reference |
| Contralateral Knee Pain (WOMAC ≥ 3) | 341/9293 (3.7%) | 1.47 (1.27, 1.70) | 0.98 (0.84, 1.15) |
| No History of Ipsilateral Knee Injury | 444/22321 (2.0%) | Reference | Reference |
| History of Ipsilateral Knee Injury | 433/9159 (4.7%) | 2.09 (1.81, 2.41) | 1.76 (1.52, 2.05) |
| No History of Contralateral Knee Injury | 518/22321 (2.3%) | Reference | Reference |
| History of Contralateral Knee Injury | 359/9159 (3.9%) | 1.64 (1.42, 1.91) | 1.44 (1.23, 1.67) |
| Bilateral ROA (1,347 participants, 335 injuries) | |||
| No Ipsilateral Knee Pain (WOMAC ≤ 2) | 124/5533 (2.3%) | Reference | Reference |
| Ipsilateral Knee Pain (WOMAC ≥ 3) | 211/4072 (5.2%) | 2.15 (1.70, 2.71) | 1.90 (1.47, 2.45) |
| No Contralateral Knee Pain (WOMAC ≤ 2) | 156/5433 (2.9%) | Reference | Reference |
| Contralateral Knee Pain (WOMAC ≥ 3) | 179/4072 (4.4%) | 1.46 (1.16, 1.83) | 1.01 (0.78, 1.30) |
| No History of Ipsilateral Knee Injury | 153/6201 (2.5%) | Reference | Reference |
| History of Ipsilateral Knee Injury | 182/3304 (5.5%) | 1.89 (1.49, 2.39) | 1.64 (1.28, 2.09) |
| No History of Contralateral Knee Injury | 168/6201 (2.7%) | Reference | Reference |
| History of Contralateral Knee Injury | 167/3304 (5.1%) | 1.83 (1.44, 2.32) | 1.66 (1.29, 2.12) |
| No ROA at All Visits (1,204 participants, 154 injuries) | |||
| No Ipsilateral Knee Pain (WOMAC ≤ 2) | 111/7866 (1.4%) | Reference | Reference |
| Ipsilateral Knee Pain (WOMAC ≥ 3) | 43/1723 (2.5%) | 1.69 (1.16, 2.45) | 1.40 (0.93, 2.10) |
| No Contralateral Knee Pain (WOMAC ≤ 2) | 116/7866 (1.5%) | Reference | |
| Contralateral Knee Pain (WOMAC ≥ 3) | 38/1723 (2.2%) | 1.47 (1.00, 2.15) | 1.19 (0.78, 1.82) |
| No History of Ipsilateral Knee Injury | 90/7366 (1.2%) | Reference | |
| History of Ipsilateral Knee Injury | 64/2223 (2.9%) | 2.13 (1.51, 3.00) | 2.00 (1.39, 2.87) |
| No History of Contralateral Knee Injury | 107/7366 (1.5%) | Reference | |
| History of Contralateral Knee Injury | 47/2223 (2.1%) | 1.41 (0.97, 2.05) | 1.18 (0.81, 1.74) |
*
In addition to the variables indicated above each model was adjusted for sex, age, and body mass index at each visit. Bold = significant odds ratios.