Significant activation (p≤0.05, FWE) in response to combined baseline painful and PA stimuli. Abbreviations: Abbreviations: PAG, periaqueductal gray; Thal, thalamus; P-Ins, posterior insula; SI, primary somatosensory cortex; SII, secondary somatosensory cortex; dACC, dorsal anterior cingulate cortex, dlPFC, dorsolateral prefrontal cortex; A-Ins, anterior insula