Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Environ Toxicol Pharmacol. 2015 Jun 23;40(1):333–341. doi: 10.1016/j.etap.2015.06.016

Figure 5. Effect of intranasal manganese on the expression of key proteins involved in dopaminergic pathway in the striatum from Hfe-deficient mice.

Figure 5

Striatum collected from mice was analyzed by western blot to determine the expression levels of tyrosine hydroxylase (A), dopamine transporter (B) and dopamine D1 (C) and D2 (D) receptors. Relative intensities of protein bands normalized to actin were determined using Image Lab (version 4.1). Empty and closed bars represent wild-type (Hfe+/+) and Hfe-deficient (Hfe−/−) mice, respectively. Data were presented as mean ± SEM (n = 4 per group) and were analyzed using two-way ANOVA, followed by post-hoc comparisons.