Figure 7. Effect of intranasal manganese on the expression of proteins involved in monoaminergic turnover in the striatum from Hfe-deficient mice.
Striatum collected from mice was analyzed by western blot to determine the expression levels of vesicular monoamine transporter (A) and catechol-O-methyltransferase (B). Relative intensities of protein bands were normalized to actin. Empty and closed bars represent wild-type (Hfe+/+) and Hfe-deficient (Hfe−/−) mice, respectively. Data were presented as mean ± SEM (n = 4 per group) and were analyzed using two-way ANOVA, followed by post-hoc comparisons.