Table 3.
Baseline characteristics and outcomes in patients with advanced ovarian cancer in relation to pre-treatment TNF-α and IL-6 ascites levels
IL-6 low | IL-6 high/TNF-α low | IL-6 high/TNF-α high | p-value | ||
---|---|---|---|---|---|
Number of patients | 34 | 18 | 18 | ||
Mean age in years | 64.5 | 57.8 | 60.7 | p=0.135 | |
| |||||
Grade | 1 | 3 | 1 | 1 | p=0.030 |
2 | 3 | 7 | 1 | ||
3 | 27 | 9 | 15 | ||
Serous % | 85.3 | 66.7 | 77.8 | p=0.266 | |
<1cm residual disease % | 75.8 | 77.8 | 77.8 | p=0.981 | |
| |||||
OS, Months | 26.1 (17.9-49.1) | 48.4 (26.5-NA) | 24.0 (13.2-34.0) | p=0.018 | |
PFS, Months | 13.8 (9.0-17.1) | 18.1 (11.9-NA) | 6.2 (5.3-12.1) | p<0.001 |
NA: survival estimate does not reach 50%; Italic added for emphasis