Table 6.
CYP2C9 & CYP2C8 frequencies in previously studied populations.
| CYP2C9 alleles frequency percentage | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Racial and ethnic group | *1 | *2 | *3 | *4 | *5 | *6 | *8 | *9 | *11 | *12 | *13 | Ref. |
| African Americans (n = 165) | 0.824 | 0.027 | 0.012 | 0.000 | 0.009 | 0.009 | 0.042 | 0.061 | 0.015 | 0.000 | 0.000 | This study |
| African American (n = 300) | 0.867 | 0.028 | 0.020 | 0.000 | 0.015 | 0.010 | 0.047 | – | 0.013 | – | 0.000 | 19 |
| Ghanaian (n = 204) | – | 0.000 | 0.000 | 0.000 | 0.000 | – | – | – | 0.020 | – | – | 21 |
| Beninese (n = 111) | 0.955 | 0.000 | 0.000 | 0.000 | 0.018 | – | – | – | 0.027 | – | – | 22 |
| Mozambican (n = 206) | – | 0.000 | 0.010 | – | 0.019 | 0.000 | 0.146 | – | 0.024 | – | – | 23 |
| Africans (n = 250) | 0.810 | 0.120 | 0.000 | – | 0.010 | 0.012 | 0.040 | 0.095 | 0.022 | 0.020 | – | 20 |
| CYP2C8 alleles frequency percentage | ||||||||||||
| *1 | *2 | *3 | *4 | *5 | *7 | *8 | *9 | *10 | *11 | *12 | ||
| African American (n = 165) | 0.806 | 0.164 | 0.018 | 0.012 | 0.000 | 0.000 | 0.000 | – | – | – | – | This study |
| African American (n = 500) | 0.878 | 0.100 | 0.010 | 0.012 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | – | 0.000 | 24 |
| Mozambican (n = 360) | 0.160 | 0.048 | 0.000 | 0.005 | 0.000 | – | – | – | – | – | – | 25 |
| Ghanaian (n = 204) | – | 0.170 | 0.000 | 0.000 | – | – | – | – | – | – | – | 21 |
(–) Allele not screened in study