Table 1. Management of clinical and screen-detected SSNs, at initial detection.

Management protocol	Referral for work-up*	3-month follow-up	6-month follow-up	1-year follow-up	No follow-up required
Fleischner (10)	Part-solid >10 mm	GGN >5 mm Part-solid ≤10 mm			GGN ≤5 mm
NCCN (22)	Part-solid ≥8 mm	GGN >10 mm Part-solid 6 -<8 mm	GGN 5-10 mm	GGN <5 mm Part-solid <6 mm
ACCP (23)	Part-solid >15 mm	Part-solid ≤15 mm		GGN >5 mm	GGN ≤5 mm
LungRADS® (7)	Part-solid; SC ≥8 mm	Part-solid ≥6 mm; SC ≥6 -<8 mm	GGO ≥20 mm Part-solid ≥6 mm; SC <6 mm	GGN <20 mm Part-solid <6 mm

ACCP, American College of Chest Physicians; GGN, ground-glass nodule, nonsolid nodule; NCCN, National Comprehensive Cancer Network; SC, solid component. *, chest CT with or without contrast, PET/CT and/or tissue sampling depending on the probability of malignancy and comorbidities.